PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 27, 2026Journal of Integrative Agriculture0 citationsOpen Access

Mapping genetic architecture of the duck serum metabolome and its contribution to complex traits1

View Full Paper
YXYang XiZYZhao YangJQJingjing Qi

Key Points

  • This research explores the heritability of duck serum metabolites and their influence on complex traits through genetic mapping.
  • Assessed heritability of duck serum metabolites with focus on class-specific differences.
  • Established mQTL that connect regulatory variants to metabolite levels and complex traits.
  • Used GBLUP model for trait prediction, integrating mQTL data.
  • Metabolites showed low overall heritability; however, amino acids and nucleotides had higher heritability.
  • Identified complete genetic pathways linking regulatory variants to metabolite abundance and traits.
  • Trait prediction accuracy improved significantly with GBLUP model integration, enhancing duck breeding potential.

Abstract

(1) Duck serum metabolites show low overall heritability, with class-specific differences; metabolites closer to gene-regulatory nodes (e.g., amino acids, nucleotides) exhibit higher heritability. (2) The mQTL bridge regulatory variants (eQTL/sQTL/apaQTL) to metabolite abundance and, in turn, to duck complex traits, clarifying the relatively complete genetic pathway. (3) Integrating mQTL information with genomic best linear unbiased prediction (GBLUP) model significantly improved trait prediction accuracy, demonstrating utility for duck breeding.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Xi et al. (2026) studied this question.

synapsesocial.com/papers/69eefd82fede9185760d430chttps://doi.org/10.1016/j.jia.2026.04.026
Ask AI
Helpful
Bookmark
Share
View Full Paper