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April 27, 2026Surgical Neurology International0 citationsOpen Access

Endovascular treatment for subarachnoid hemorrhage during pregnancy followed by minimum approaches for cerebral vasospasm

RMRyosuke MaeokaHOHiroyuki OhnishiRMRyosuke Matsuda

Key Result

Endovascular treatment followed by minimum required prevention for cerebral vasospasm in a pregnant woman with subarachnoid hemorrhage resulted in a Glasgow outcome scale score of 5 and delivery of a healthy infant.

Key Points

  • To explore effective management strategies for subarachnoid hemorrhage in pregnant women.
  • Case study of a 36-year-old pregnant woman with SAH treated with endovascular treatment (EVT).
  • Utilized digital subtraction angiography to identify a small saccular aneurysm.
  • Administered minimum pharmacological treatments for cerebral vasospasm: fasudil hydrochloride, aspirin, ozagrel sodium.
  • Patient had a Glasgow outcome scale score of 5 at discharge after EVT.
  • Successful delivery of a healthy infant at 37 weeks with no abnormalities at 1 year.
  • No oral medications required 25 days post-aneurysm rupture.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

Does endovascular treatment and minimum pharmacotherapy for cerebral vasospasm improve maternal and fetal outcomes in a pregnant woman with subarachnoid hemorrhage?

P
Population
1 pregnant woman (36-year-old at 24 weeks of gestation) with subarachnoid hemorrhage (SAH) due to a ruptured small saccular aneurysm on the posterior communicating artery.
I
Intervention
Endovascular treatment (EVT) with balloon-assisted coil embolization, followed by minimum required prevention and treatment of cerebral vasospasm using fasudil hydrochloride, aspirin, and ozagrel sodium, and percutaneous transluminal angioplasty (PTA) for symptomatic vasospasm.
O
Outcome
Maternal and fetal clinical outcomes (Glasgow outcome scale score, delivery success, infant health at 1 year)

Endovascular treatment with balloon-assisted coil embolization and carefully selected minimal pharmacotherapy for vasospasm can be safely performed in pregnant women with subarachnoid hemorrhage.

Limitations

  • Single case report
  • Lack of definitive treatment guidelines for subarachnoid hemorrhage during pregnancy

Abstract

Background: Managing subarachnoid hemorrhage (SAH) during pregnancy is challenging due to its rarity, lack of definitive treatment guidelines, and significant concerns regarding both surgical and obstetric management for the pregnant mother and fetus. Treatment methods and medications must be carefully selected, considering the possibility of adverse effects and safety for both the pregnant mother and fetus. We present the case of a pregnant woman with SAH who underwent endovascular treatment (EVT) followed by minimum approaches for cerebral vasospasm prevention and treatment. Case Description: A 36-year-old female at 24 weeks of gestation presented with a headache without neurological deficits. Magnetic resonance imaging on admission showed SAH with diffuse clotting in the basal cistern. Digital subtraction angiography identified a small saccular aneurysm. We performed EVT, followed by minimum required prevention and treatment of cerebral vasospasm using fasudil hydrochloride, aspirin, and ozagrel sodium, as these agents seem to be associated with fewer adverse effects at 26 weeks of gestation. The patient exhibited a Glasgow outcome scale score of 5 at discharge, with no oral medications at 25 days after aneurysm rupture. The pregnancy progressed favorably, and a healthy infant was successfully delivered through a scheduled cesarean section in gestational week 37. The child showed no abnormalities at 1 year of age. Conclusion: We reported the case of a pregnant patient with SAH who underwent EVT, followed by the minimum required prevention and treatment for cerebral vasospasm. Clinicians should carefully select the medical approaches, including pharmacotherapies for both pregnant women with SAH and the fetus, considering radiation exposure and medication risks.

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Cite This Study

Maeoka et al. (2026) conducted a case report in Subarachnoid hemorrhage during pregnancy (n=1). Endovascular treatment (EVT) and minimum approaches for cerebral vasospasm was evaluated on Clinical and fetal outcome. Endovascular treatment followed by minimum required prevention for cerebral vasospasm in a pregnant woman with subarachnoid hemorrhage resulted in a Glasgow outcome scale score of 5 and delivery of a healthy infant.

synapsesocial.com/papers/69eefd82fede9185760d4318https://doi.org/10.25259/sni_96_2026
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