How does heart rate affect the frequency of premature ventricular complexes in patients with mitral valve prolapse?
Patients with mitral valve prolapse (MVP)
Premature ventricular complex (PVC) profile in relation to heart ratesurrogate
In patients with mitral valve prolapse, premature ventricular complexes are predominantly fast-heart-rate-dependent, suggesting a catecholamine-sensitive trigger mechanism for ventricular arrhythmias.
Fast-heart-rate-dependent-PVC was the most common PVC profile in MVP patients, and slow-heart-rate-dependent-PVC was rare. These findings suggest a catecholamine-sensitive mechanism acting as trigger for ventricular arrhythmias in MVP patients.
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Cecilie Bugge
Christian K Five
Tariq Ahmed
IJC Heart & Vasculature
University of Oslo
Oslo University Hospital
Institutt for Eksperimentell Medisinsk Forskning
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Bugge et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69eff939bce9831ba4f735e8 — DOI: https://doi.org/10.1016/j.ijcha.2026.101925