PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 28, 2026Cardiovascular Research0 citations

Differential metabolomic prediction of outcomes in HFpEF and HFrEF: a prospective international multi-ethnic cohort study

View Full Paper
LWLik Hang WuLPLeroy Sivappiragasam PakkiriJTJasper Tromp

Key Points

  • This research aims to identify differential metabolic signatures associated with heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) to improve risk assessment and treatment strategies.
  • Prospective international multi-ethnic cohort study
  • Analysis of metabolic signatures associated with HFpEF and HFrEF
  • Focus on metabolic inflammation and energy metabolism pathways
  • Identified distinct metabolic profiles for HFpEF and HFrEF patients
  • Enhanced risk stratification based on metabolic signatures
  • Highlighted potential therapeutic targets for intervention

Abstract

Differential metabolic signatures tied to metabolic inflammation in HFpEF and impaired energy metabolism in HFrEF enhance risk stratification and point to therapeutic targets.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69f04e9b727298f751e727a1https://doi.org/10.1093/cvr/cvag090
Ask AI
Helpful
Bookmark
Share
View Full Paper