Intestinal motility shapes spatiotemporal patterns of enterohemorrhagic Escherichia coli colonization and virulence gene expression in the host gut

Key Points

• This research focuses on the role of intestinal motility in shaping the behavior of enterohemorrhagic Escherichia coli in the gut.
• Investigated the relationship between intestinal motility and E. coli behavior.
• Analyzed patterns of colonization and gene expression related to virulence.
• Observed spatiotemporal patterns in a host gut model.
• Intestinal motility significantly influences spatiotemporal patterns of E. coli colonization.
• Altered motility is linked to changes in virulence gene expression.
• Findings highlight the importance of intestinal motility in the understanding of pathogenesis.