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April 29, 2026RSC Advances3 citationsOpen Access

Nitrogen-Containing Drugs in 2025: Synthesis and Therapeutic Applications

Nitrogen-containing FDA-approved drugs in 2025: synthesis, significance and therapeutic applications

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Authors

CJChetna JadalaSMShweta MishraGPGal Reddy Potuganti

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Overview

This overview highlights nitrogen compounds' significance in pharmaceuticals, demonstrating their therapeutic applications and structural motifs.

Key Points

  • The aim is to explore the role of nitrogen-containing heterocycles in pharmaceuticals and their therapeutic significance.
  • Review of nitrogen-containing FDA-approved drugs in 2025
  • Analysis of synthetic pathways for N-Hets
  • Assessment of therapeutic applications of these compounds
  • Nitrogen-containing heterocycles are key structural motifs in over 85% of active small molecules
  • N-Hets demonstrate versatility in pharmaceutical development
  • Significant potential for therapeutic applications identified

Cite This Study

Jadala et al. (2026) studied this question.

synapsesocial.com/papers/69f154c0879cb923c49450d8https://doi.org/10.1039/d6ra00737f
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1RECENT ADVANCES IN THE SYNTHESIS AND PHARMACOLOGICAL APPLICATIONS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS2026
  2. 2Asymmetric Hydrogenation of <i>N</i> -Heterocycles for Pharmaceutical Intermediates: Synthetic Strategies and Theoretical Perspectives2025
  3. 3A Review on the Synthesis and Biological Evaluation of N-containing Heterocyclic Derivatives2026
  4. 4Advances in Continuous‐Flow Synthesis of Nitrogen‐Containing Heterocycles Through Sequence Transformations in the Past Decade (2016–2025)2025
  5. 5Natural Products Containing an N–N Bond (2013–2025)2026