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April 29, 2026Microbial Genomics0 citationsOpen Access

bifidoAnnotator: fine-grained annotation of bifidobacterial glycoside hydrolases for human milk glycan utilization

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NPNicholas PucciDMDaniel R. Mende

Key Points

  • This research aims to enhance annotation workflows for bifidobacterial glycoside hydrolases related to human milk glycan utilization.
  • Developed an annotation tool called bifidoAnnotator.
  • Assessed the computational performance and efficiency of the tool.
  • Characterized strain-level functional diversity in bifidobacteria.
  • bifidoAnnotator showed superior performance in high-throughput annotation tasks.
  • Enabled detailed characterization of glycoside hydrolases involved in human milk glycan metabolism.

Abstract

's superior performance and computational efficiency represent a meaningful advance in high-throughput genomic annotation workflows, enabling detailed characterization of strain-level functional diversity in bifidobacterial HMG metabolism.

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Cite This Study

Pucci et al. (2026) studied this question.

synapsesocial.com/papers/69f154e0879cb923c4945374https://doi.org/10.1099/mgen.0.001702
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