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April 29, 2026npj Digital Medicine0 citationsOpen Access

Fourier Kolmogorov-Arnold Network integrated into BioBERT-based model for Biomedical Named Entity Recognition

立林立也 林WYWu YanXXXiaojun Xie

Key Points

  • The study aims to enhance biomedical named entity recognition (BioNER) using an integrated model approach.
  • Developed FRKAN-BioNER by combining BioBERT with Fourier Kolmogorov-Arnold Network (FourierKAN) architecture.
  • Evaluated the model's performance on nine public datasets measuring F1-scores.
  • Addressed limitations of traditional neural networks to improve expressiveness and trainability.
  • FRKAN-BioNER achieved F1-scores ranging from 78.58% to 93.12% across various datasets.
  • Outperformed several state-of-the-art BioNER models, indicating a robust performance.
  • Potential for enhancing clinical text processing and biomedical literature mining.

Abstract

Biomedical Named Entity Recognition (BioNER) extracts entities such as diseases, drugs, and genes from biomedical texts, which are often dense in domain-specific terms and complex semantics. Here, we present FRKAN-BioNER, a model designed to improve the efficiency of data mining in the biomedical field and support the development of precision medicine knowledge graphs. FRKAN-BioNER integrates BioBERT (Bidirectional Encoder Representations from Transformers for Biomedical Text Mining) with the Fourier Kolmogorov-Arnold Network (FourierKAN). The KAN architecture addresses limitations in traditional neural networks, improving model expressiveness and trainability. The model achieved F1-score of 84.80%, 93.12%, 90.02%, 82.10%, 87.90%, 83.14%, 78.58%, 89.93%, and 90.87% across nine public datasets. These results demonstrate that FRKAN-BioNER outperforms several prior state-of-the-art methods. Furthermore, its innovative architecture may hold potential for improving the efficiency of BioNER-relevant clinical text processing and could help accelerate knowledge mining from large-scale biomedical literature.

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Cite This Study

林 et al. (2026) studied this question.

synapsesocial.com/papers/69f19ff5edf4b46824806a3fhttps://doi.org/10.1038/s41746-026-02677-4
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