Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 30, 2026Asian Journal of AndrologyOpen Access

Predicting the upgrading of the International Society of Urological Pathology Grade Group in nonclinically significant prostate cancer: a multicenter observational study

View Full Paper
Ask AI
Bookmark
Share

Authors

LZLing ZhouSLShiyan LiZWZhang-Yun Wang

Discussion

Loading...

Member takes

Overview

Observational study identifies MRI and ultrasound techniques as key predictors of ISUP Grade Group upgrading in prostate cancer biopsies.

Key Points

  • The research aims to identify predictors of ISUP Grade Group upgrading in nonclinically significant prostate cancer post-biopsy.
  • Conducted a multicenter observational study
  • Analyzed clinical data from 231 patients undergoing TRUS-guided biopsy and radical prostatectomy
  • Applied univariate and multivariate logistic regression analyses
  • Evaluated diagnostic efficiency using receiver operating characteristic curves
  • Identified magnetic resonance imaging and contrast-enhanced ultrasound as independent predictors
  • Demonstrated the highest diagnostic performance with an AUC of 0.738
  • Noted MRI showed superior predictive efficacy in smaller prostate volumes compared to CEUS

Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/69f2a42a8c0f03fd677633d1https://doi.org/10.4103/aja2025115
View Full Paper
Ask AI
Bookmark
Share