Primary hepatic neuroendocrine tumour in a child

Abstract Primary hepatic neuroendocrine tumour (PHNET) is an exceptionally rare neoplasm, accounting for approximately 0.3% of all neuroendocrine tumours. It presents with non specific clinical and radiological features, making pre operative diagnosis difficult. Differentiation from other paediatric liver lesions, such as hepatoblastoma, haemangioma and hepatocellular carcinoma, is challenging. We report the rare case of PHNET in a 9 year old boy who presented with abdominal pain and vomiting. Routine laboratory investigations, including liver function tests and serum alpha fetoprotein levels, were within the normal limits. Radiological evaluation suggested a diagnosis of sclerosed hepatic haemangioma. Definitive diagnosis was established by histopathological examination and immunohistochemistry. Surgical resection was performed, which remains the mainstay of treatment. The post operative course was uneventful and regular follow up. This case highlights the diagnostic difficulty of PHNET and underscores the importance of histopathological evaluation for accurate diagnosis and appropriate management.