Comparative Analysis of Greenlight LaserPhotovaporization and Holmium Laser Enucleation ofthe Prostate for Benign Prostatic Hyperplasia Surgery
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Overview
Randomized trial compares urinary flow and safety outcomes in patients undergoing prostate surgery.
Key Points
This study aims to compare the efficacy and safety of GreenLight laser photovaporization and Holmium laser enucleation for benign prostatic hyperplasia.
220 patients underwent endoscopic prostate surgery, divided evenly between PVP and HoLEP.
Preoperative, intraoperative, and postoperative variables measured included Qmax, PSA reduction, and adverse effects.
Statistical analysis employed Fisher’s exact, Student’s t, and Mann–Whitney U tests.
HoLEP group showed significantly higher Qmax (31.31 mL/s) compared to PVP (24.48 mL/s, p = 0.014).
Greater reduction in PSA was observed in HoLEP (94.54%) versus PVP (47.11%, p = 0.008).
Urgency was lower in HoLEP group (0.9% vs. 11.8%, p = 0.001); however, urethral stricture rates were higher (4.5% HoLEP vs. 0.9% PVP, p > 0.05).