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April 30, 2026Brain TopographyOpen Access

Bifocal Beta-frequency Transcranial Alternating Current Stimulation Enhances Somatosensory Spatial Discrimination

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Authors

RSRyoki SasakiSKSho KojimaTHTaiga Hiraga

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Overview

Randomized trial examines the effects of bifocal tACS on spatial discrimination in healthy adults, highlighting potential therapeutic implications.

Key Points

  • This research investigates how bifocal beta-frequency tACS influences tactile two-point discrimination by targeting specific cortical networks.
  • Thirty healthy adults underwent five sessions including MRI, MEG, and three tACS sessions.
  • tACS was administered to the S1–SPL or S1–AG networks at each participant's individual frequency.
  • TPD was assessed at multiple distances before, during, and after stimulation.
  • Significant improvements in TPD at 3.0, 3.5, and 5.0 mm distances with S1–SPL tACS (all P < 0.049).
  • Improvements noted at 3.5 mm distance with S1–AG tACS (all P < 0.046).
  • Sham condition showed no significant effects; electric field modeling confirmed effective targeting.

Cite This Study

Sasaki et al. (2026) studied this question.

synapsesocial.com/papers/69f2f0e31e5f7920c6386e63https://doi.org/10.1007/s10548-026-01206-6
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