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April 30, 2026IDCasesOpen Access

Adult case of chronic granulomatous disease with left axillary lymphadenitis caused by Mycobacterium tuberculosis var. BCG over 40 years post-vaccination: a case report

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Authors

KNKeiji NakamuraNINoriko IwamotoTNTakato Nakamoto

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Overview

Case report describes lymphadenitis due to BCG in an adult with CGD, suggesting long-term risks post-vaccination.

Key Points

  • To evaluate the rare occurrence of BCG-related lymphadenitis in an adult with chronic granulomatous disease.
  • Case report of an adult Japanese man with CGD
  • Lymph node biopsy identified Mycobacterium tuberculosis var. BCG
  • Patient treated with antimicrobial agents and followed by interferon-gamma prophylaxis.
  • Lymphadenitis developed 42 years post-BCG vaccination
  • Successful treatment with two years of antimicrobial therapy
  • No relapse of lymphadenitis after interferon-gamma prophylaxis.

Cite This Study

Nakamura et al. (2026) studied this question.

synapsesocial.com/papers/69f2f1771e5f7920c63871b4https://doi.org/10.1016/j.idcr.2026.e02587
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