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May 1, 20262 citations

Discovery of a Structurally Distinct Acetylenase in the Biosynthesis of Mangotoxin.

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EBEdward D. BaddingEKElijah N. KissmanSVStefan V Velculescu

Key Points

  • To identify and characterize a novel acetylenase involved in the biosynthesis of mangotoxin.
  • Characterization of acetylenase structure and function
  • Comparison with known HDOs to explore mechanisms
  • Identified a unique acetylenase that operates through a new chemical mechanism
  • Expanded understanding of HDO chemistry beyond previously established pathways

Abstract

)-H bonds may utilize a mechanism distinct from other HDOs and expands the scope of known HDO chemistry.

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Cite This Study

Badding et al. (2026) studied this question.

synapsesocial.com/papers/69f4427a967e944ac5565ffdhttps://doi.org/10.1021/jacs.5c21680
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