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May 1, 20260 citationsOpen Access

Bowel No 5 - Functional Gastro-Intestinal Disorders v Dysfunctional Human Beings; Micromanagement of Milieu Interior Part Ii – Sublata Causa, Tollitur Effectus (Removing Cause, Removes Effect)

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*F*1,2,3Om Prakash Sudrania, MBBS, MS, FRCSEd, FICS

Key Points

  • The aim is to explore the subtle causes of nonorganic gastrointestinal disorders and their effects.
  • Clinical history taking and classification of Gastroesophageal Reflux Disease (GERD) and Non-Erosive Reflux Disease (NERD) are examined.
  • Discussion on the modulation of gastric acidity and gut biophysiopathology is presented.
  • Identified several factors contributing to functional gastrointestinal disorders including gut motility and microbiota.
  • Suggest the need for better understanding of underlying causes rather than just focusing on symptoms.

Abstract

Humans or Homo sapiens sapiens are said to suffer from Nonorganic Gastro-Intestinal Disorders (NGIDs) classed as ―Functional Gastro-Intestinal Disorders (FGIDs)‖. In this issue, subtle issues of clinical history taking, classification of GERD/NERD, role of gastric acidity and its modulation; humans are not ruminants, they are designated omnivores turned opportunistic carnivores, gut fundamental biophysiopathology, eg, gut motility, microbiota, visceral sensitivity, gut mucosal immune system, altered central, autonomic and enteric nervous system processing etc, which are not cause but effects of a subtle cause are discussed.

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Cite This Study

*1,2,3Om Prakash Sudrania, MBBS, MS, FRCSEd, FICS (2026) studied this question.

synapsesocial.com/papers/69f442d4967e944ac55664bfhttps://doi.org/10.5281/zenodo.19884317
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