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Synapse
May 1, 2026Cancer Discovery0 citations

Daraxonrasib Continues Victory Lap

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Key Points

  • The aim is to evaluate the safety and effectiveness of daraxonrasib in treating pancreatic ductal adenocarcinoma.
  • Conducted two phase I/II studies
  • Analyzed data from previously announced phase III study
  • Daraxonrasib shows superior performance compared to standard treatments in phase III
  • Indicates potential for sustained patient responses
  • Suggests daraxonrasib could be a breakthrough targeted therapy for pancreatic cancer

Abstract

Results from two separate phase I/II studies investigating the pan-RAS inhibitor daraxonrasib suggest it is safe and effective for patients with pancreatic ductal adenocarcinoma, building on recently announced data showcasing the drug's superior performance in a phase III study. Together, these new data are an exciting sign that daraxonrasib could become the first targeted pancreatic cancer therapy to spur sustained responses.

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Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/69f443e8967e944ac5566f8fhttps://doi.org/10.1158/2159-8290.cd-nw2026-0046
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