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May 1, 2026NEJM Evidence0 citations

A 65-Year-Old Woman with Fatigue and Leg Pain

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NENiloufar EbrahimiAAAmir AbdipourPBPravir Baxi

Key Points

  • To collaboratively evaluate the case of a 65-year-old woman presenting with fatigue and leg pain.
  • Case presentation in a morning report format
  • Use of physical examination and clinical testing
  • Development of differential diagnosis throughout the clinical course
  • A refined differential diagnosis was developed based on the clinical findings and tests
  • The final diagnosis was determined after collaborative discussion
  • The clinical process highlighted the importance of thorough patient history and examination

Abstract

AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry on this tradition by presenting a patient's chief concern and story, inviting the reader to develop a differential diagnosis and discover the diagnosis alongside the authors of the case. This report examines the story of a 65-year-old woman who presented to the emergency department with fatigue and progressively worsening leg pain. Using questions, physical examination, and testing, an illness script for the presentation emerges. As the clinical course progresses, the differential is refined until a diagnosis is made.

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Cite This Study

Ebrahimi et al. (2026) studied this question.

synapsesocial.com/papers/69f44488967e944ac55677a2https://doi.org/10.1056/evidmr2500335
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