Flow Gradients in Severe Aortic Stenosis and Preserved Ejection Fraction: A 10-Year Transcatheter Aortic Valve Replacement Study

Background: There are limited and conflicting data on the long-term outcomes in normal-flow low-gradient (NFLG) and paradoxical low-flow low-gradient (pLFLG) aortic stenosis (AS) following transcatheter aortic valve replacement (TAVR). Methods: ). The primary outcome was all-cause mortality at 1 and 5 years. Results: = .06). There was no significant difference in survival between the 3 groups at 5 years post-TAVR. Conclusions: In patients who undergo TAVR, those with a pLFLG pattern of AS have a worse 1-year survival, but similar 5-year survival when compared with traditional HGAS AS. There was no significant difference in survival in patients with NFLG AS when compared with HGAS at 1 and 5 years post-TAVR.