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May 2, 20260 citations

Return of Individual Research Information in the Parkinson's Progression Markers Initiative.

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TTThomas F TropeaKBKathryn BrodkinMBMichael C. Brumm

Key Points

  • The aim is to explore the impact of returning individual research information to participants in the Parkinson's Progression Markers Initiative.
  • Implemented two initiatives: Return of Research Information program and Randomized Disclosure Assessment.
  • Focused on longitudinal clinical assessments and biomarker research data.
  • Participants' requests for data sharing were considered in planning the disclosure processes.
  • Both initiatives empower participants to access their data.
  • Gathering insights on the impact of data disclosure on participants and study quality.
  • Prioritization of research information sharing enhances participant engagement.

Abstract

The commitment of Parkinson's Progression Markers Initiative participants to longitudinal comprehensive clinical and biomarker research assessment is key to its success in acquiring high quality data. As the study has evolved, it has become clear that return of research information to participants should be prioritized to provide participants with their data as they have consistently and reasonably requested. The Parkinson's Progression Markers Initiative is committed to responsible sharing of individual research information with study participants. Two initiatives dedicated to results disclosure were simultaneously implemented: the Return of Research Information program and the Randomized Disclosure Assessment in the Parkinson's At-Risk Cohort clinical trial. These are pioneering studies on research information sharing. These initiatives empower participants and will provide valuable insights on the impact that disclosure may have on participants and study data. ANN NEUROL 2026.

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Cite This Study

Tropea et al. (2026) studied this question.

synapsesocial.com/papers/69f594e171405d493afffca4https://doi.org/10.1002/ana.78228
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