PURPOSE: Up to 4% of adults will develop strabismus in their lifetime. The most common surgical intervention involves adjusting the length of one or more extraocular muscles to correct the angular deviation. This correction depends on surgical expertise and statistical reference tables, which often fail to yield optimal results for patients with atypical eye morphology. Our work proposes a physics-based modeling approach to personalized surgical planning, accounting for patient-specific eye anatomy. METHODS: We built a physics-based simulator of the eye and its muscles, incorporating patient-specific geometry and Hill-type muscle biomechanics. We solve an optimization problem to find the surgical dosage that minimizes angular deviation. The model is implemented as a fully differentiable simulation, enabling efficient optimization. We validated the framework by comparing its predictions with standard surgical tables for emmetropic eyes before applying it to anatomically atypical virtual patients. RESULTS: Our model's predictions for emmetropic eyes were first validated, demonstrating a strong fit with standard surgical tables. More importantly, for high-myopia models, the framework computed a clinically significant increase in the required surgical dosage compared to standard eyes. This computed recession difference is highly relevant as surgical plans are adjusted in 0.5 mm increments. CONCLUSION: Our results show that our model provides a calibrated surgical plan that, unlike standard tables, also accounts for pathologies involving atypical eye shapes. This patient-specific model represents a step toward personalized surgical planning, with the potential to improve dosage accuracy and surgical outcomes for atypical cases.
Harsigny et al. (2026) studied this question.