Randomized trial examines postoperative delirium prevention in older surgical patients, indicating the need for targeted strategies.
Key Points
This research aims to improve the prevention of postoperative delirium (POD) and cognitive decline in older surgical patients through precision medicine approaches.
Evaluation of existing prevention standards focusing on multicomponent, non-pharmacological bundles.
Assessment of EEG-guided anesthesia trials and screening uptake in clinical settings.
Identification of gaps in implementation of screening pathways and vulnerability assessment tools.
Screening for POD prevention remains below 10%, hindering effective brain care.
Current multicomponent bundles are insufficiently translated into precise interventions due to existing gaps.
Biomarkers and individualized monitoring could enhance risk stratification but require integration into broader care protocols.