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May 3, 2026

Origins and drivers of self-reactive B cells in autoimmune disease.

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Authors

ALAdrian Y S LeeQSQian ShenJRJoanne H. Reed

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Overview

Research Highlight reveals origins and drivers of self-reactive B cells in autoimmune disease, indicating potential pathways for treatment.

Key Points

  • This article reviews recent studies on self-reactive B cells to understand their origins and contributions to autoimmune disease.
  • Reviewed four articles published in 2025 on self-reactive B cells.
  • Investigated self-reactive B cells in human peripheral blood and murine models.
  • Explored the role of viral and genetic factors in the development of self-reactive B cells.
  • Identified new insights into the mechanisms driving self-reactive B cells
  • Highlighted the role of genetic and viral factors in autoimmune disease pathogenesis.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69f6e5f38071d4f1bdfc6975https://doi.org/10.1111/imcb.70128
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