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May 3, 20260 citations

Tubed or tubeless insulin pumps? A retrospective real-world analysis of national French health data.

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HHHelene HanaireAVAlexandre VimontABAlice Bonin

Key Points

  • This study examines treatment persistence among people with type 1 diabetes using tubed or tubeless insulin pumps in France.
  • Retrospective analysis of national health data from people with insulin claims in France.
  • Evaluated insulin therapy initiation rates and persistence in pump users.
  • Compared rates of therapy discontinuation between tubed and tubeless pump users.
  • Among pump users (n=61,251), tubeless pump users had higher persistence rates (unadjusted HR 0.60, 95% CI 0.58 to 0.61).
  • Tubeless pump users had a 40% lower risk of treatment discontinuation (p<0.0001).
  • Tubeless pumps led to fewer therapy changes within 12 months compared to tubed pumps.

Abstract

BACKGROUND: Tubeless insulin pumps, introduced in France in 2016, have been associated with higher user satisfaction than tubed pumps, primarily due to reduced interference with daily tasks. Whether this translates to greater treatment persistence remains uncertain. This study evaluates persistence among people with type 1 diabetes initiating tubed or tubeless pump therapy in France. METHODS: tests. RESULTS: Among 1 241 624 people with insulin claims, 233 874 had type 1 diabetes. Of these, 39% (n=90 362) initiated insulin therapy during the study period; 32% started and remained on multiple daily injections (excluded), and 68% initiated pump therapy. Among pump users (n=61 251), 51% used a tubed pump, 67% a tubeless pump, and 18% initiated both types sequentially. People initiating tubeless compared with tubed pumps had higher persistence rates (unadjusted HR 0.60, 95% CI 0.58 to 0.61) and a 40% lower risk of discontinuation (p<0.0001), consistent with the adjusted model (HR 0.59, 95% CI 0.57 to 0.61). Tubeless pumps were also associated with fewer changes from one therapy to another within 12 months. Treatment changes rose for tubed pump users after tubeless pumps entered the French market. CONCLUSIONS: Higher persistence and lower therapy changes among tubeless pump users underscore its sustained benefit for diabetes management.

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Cite This Study

Hanaire et al. (2026) studied this question.

synapsesocial.com/papers/69f6e6648071d4f1bdfc70f8https://doi.org/10.1136/bmjdrc-2025-005860
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