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May 4, 2026SHILAP Revista de lepidopterología0 citationsOpen Access

Microneedle-Guided Monitoring and Therapy for Chronic Limb-Threatening Ischemia

Microneedle-guided monitoring and therapy in chronic limb-threatening ischemia

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Authors

ZZZhen ZhangXZXiao-Dan ZhaoAAAikeremujiang Ahamujiang

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Overview

Mini review explores microneedle techniques to monitor and treat chronic limb-threatening ischemia, implying potential to improve patient outcomes.

Key Points

  • To evaluate microneedle technology for monitoring and local therapy in chronic limb-threatening ischemia (CLTI).
  • Synthesized evidence linking core markers (oxygenation, lactate, pH) to ischemic pathophysiology
  • Outlined microneedle sensing approaches for monitoring these markers
  • Summarized local delivery designs that facilitate staged care and improve patient outcomes.
  • Microneedle systems can provide continuous monitoring of ischemic markers, improving early detection
  • Local therapies using these systems stabilize the microenvironment and help control infection
  • Key barriers include calibration challenges during prolonged use and integration into clinical practice.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69f836aa3ed186a739980ec1https://doi.org/10.3389/fcell.2026.1824311
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