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May 4, 2026SHILAP Revista de lepidopterologíaOpen Access

A novel music-based real-time fMRI neurofeedback interface modulates interhemispheric connectivity and enhances mood

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Authors

ASAlexandre SayalASAlexandre SayalJPJoão Pereira

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Overview

Randomized trial demonstrates improved mood and connectivity modulation using a music-based neurofeedback interface.

Key Points

  • This study aims to explore the efficacy of a music-based neurofeedback interface in modulating interhemispheric connectivity and enhancing mood.
  • Participants (N=22) performed motor imagery of finger-tapping with real-time music feedback during a 50-minute fMRI session.
  • The study included four neurofeedback runs: two with active music feedback and two with sham feedback.
  • Pre- and post-session questionnaires assessed mood, musical background, and subjective feedback experiences.
  • Participants successfully modulated interhemispheric connectivity using the music-based interface.
  • Active neurofeedback led to stronger network recruitment in the insula, putamen, and other relevant brain regions, compared to sham feedback.
  • Participants reported a decrease in tension and overall mood improvement after the session.

Cite This Study

Sayal et al. (2026) studied this question.

synapsesocial.com/papers/69f836aa3ed186a739980f1ehttps://doi.org/10.3389/fpsyt.2026.1757213
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