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May 4, 2026

Global distribution of mcr-carrying bacteria: an analysis of genomic data.

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Authors

KDKomla Mawunyo DossouviFSFábio Parra SelleraEIEphraim Ehidiamen Ibadin

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Overview

Database mining identifies mcr-carrying genomes across regions, indicating a global health threat.

Key Points

  • The study aims to analyze the global distribution of mcr-carrying bacteria based on genomic data from the NCBI database.
  • Database mining of the NCBI Pathogen Detection database for mcr-carrying genomes until June 2025.
  • Descriptive analysis calculating percentages of mcr variant occurrence across different parameters.
  • Assessment of geographical distribution, ecosystems, and temporal trends in mcr-carrying genomes.
  • Out of 2,422,739 genomes, 18,785 (0.78%) carried mcr variants, with mcr-1.1 and mcr-9.1 being the most common subvariants.
  • Mcr-1.1 was predominant in Asia and Europe, while mcr-9.1 was most frequent in America and Oceania.
  • 3.8% of mcr-carrying genomes harbor multiple mcr genes, underscoring the need for monitoring.

Cite This Study

Dossouvi et al. (2026) studied this question.

synapsesocial.com/papers/69f836d93ed186a739980f67https://doi.org/10.1186/s12920-026-02383-w
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