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May 6, 2026Journal of Pediatric Gastroenterology and Nutrition0 citations

Decision aid reduces caregivers' preference for acid‐suppressive medication in infants with symptoms suggestive of reflux

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AGAnna de GeusMLMarinde van LennepQDQuirine M. van Dellen

Key Points

  • Evaluate the impact of a decision aid on caregivers' preferences for acid-suppressive medication for infants with gastroesophageal reflux symptoms.
  • Included infants under 18 months referred to pediatric outpatient clinics with symptoms of gastroesophageal reflux.
  • Provided caregivers with a decision aid detailing gastroesophageal reflux and treatment options.
  • Assessed treatment preferences and decision certainty before and after using the decision aid.
  • Preference for acid-suppressive medication decreased significantly from 58% to 43% after decision aid use and to 11% post-visit.
  • Mean Decisional Conflict Scale score dropped from 47.2 to 34.4 after using the decision aid and further to 19.0 post-visit, indicating improved decision certainty.

Abstract

OBJECTIVES: Caregivers of infants with symptoms suggestive of gastroesophageal reflux (GER), such as regurgitation and excessive crying, often feel uncertain and seek treatment, though it is usually unnecessary. This study evaluated the effect of a decision aid on reducing caregivers' preference for acid suppressive medication for infants referred because of potential GER symptoms and its effect on their decision certainty. METHODS: Infants (<18 months) referred to pediatric outpatient clinics with symptoms suggestive of GER were included. The decision aid provided information on GER(D) and three treatment options: lifestyle advice, thickened feeding, and acid-suppressive medication. Caregivers completed questionnaires assessing treatment preference and decision certainty before (T1a) and after using the decision aid (T1b), and after the outpatient visit (T2). Decision certainty was assessed using the Decisional Conflict Scale (DCS). RESULTS: A total of 110 infants were included (median age 4 months interquartile range 2-6; 48% female; 78% general hospital). Pre-visit questionnaires (T1a, T1b) were completed by 79 caregivers (72%) and 53 (48%) also completed T2. Preference for acid-suppressive medication decreased from 46/79 (58%) at T1a to 34/79 (43%) at T1b (p < 0.05), and to 6/53 (11%) at T2 (p < 0.001). Mean DCS-score (scale 0-100) decreased from 47.2 (standard deviation SD 16.1) at T1a to 34.4 (SD 17.4) at T1b, and to 19.0 (SD 12.3) post-visit (p < 0.001), indicating improved decision certainty. CONCLUSIONS: The decision aid reduced caregivers' preference for acid-suppressive treatment in infants with symptoms suggestive of GER and increased decision certainty. This supports the potential role of a decision aid in promoting appropriate care.

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Cite This Study

Geus et al. (2026) studied this question.

synapsesocial.com/papers/69fa8e8904f884e66b530d3ahttps://doi.org/10.1002/jpn3.70451
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ELECTRONIC HEALTH RECORD CLINICAL DECISION SUPPORT TOOL IMPROVES AMBULATORY REFLUX TESTING PRACTICES2026 · 1 citations
  2. 2Efficacy and safety of non-pharmacological interventions for gastroesophageal reflux and gastroesophageal reflux disease in children: a systematic review2026
  3. 3Acid Suppression in Mild‐Moderate Laryngomalacia Without <scp>GERD</scp>: A Randomized Controlled Trial2025
  4. 4GERD management in neonatal ICU infants: study protocol for a randomized controlled trial comparing maturation, added rice starch formula and proton pump inhibitors2026
  5. 5Comparative Analysis of Pharmacological Treatments and Lifestyle Modifications for Managing Gastroesophageal Reflux Disease in Infants: A Literature Review2025