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May 6, 20260 citationsOpen Access

Formulation and Evaluation of Bilayer Tablets for Sustained Release of Saxagliptin

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AJAnkit Pal*, Anil Nagar, Dr. Umesh Kumar Jain

Key Points

  • To formulate bilayer tablets that facilitate the sustained release of saxagliptin.
  • Developed bilayer tablets incorporating saxagliptin and other active pharmaceutical ingredients.
  • Modified drug layer surface area using sandwiching techniques.
  • Implemented inactive layers to create swellable and erodible barriers for modified drug release.
  • Bilayer tablets demonstrated effective sustained release of saxagliptin.
  • Surface area modifications successfully controlled the drug release rate.

Abstract

In bilayer tablet A single or two different active pharmaceutical ingredients can be incorporated.They are also used for the separation of incompatible active pharmaceutical ingredients.The surface area of drug layer is modified by sandwiching. It can be controlled by one or two inactive layers and make them to achieve the swellable (or) erodible barriers for modified release. It is used for the fixation of a combination of different active pharmaceutical ingredients. Life-cycle of the drug product is increased

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Ankit Pal*, Anil Nagar, Dr. Umesh Kumar Jain (2026) studied this question.

synapsesocial.com/papers/69fa980604f884e66b531e1chttps://doi.org/10.5281/zenodo.20019734
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