Retrospective case-control study shows albumin and inflammatory indices predict adverse perinatal outcomes in preeclampsia, indicating their clinical relevance.
Key Points
To compare albumin-related indices between preeclamptic and normotensive pregnancies and evaluate their association with adverse perinatal outcomes.
Retrospective case-control study with 186 preeclamptic patients and 186 healthy controls matched for demographic factors
Comparison of laboratory parameters and calculated indices at delivery
Logistic regression models to identify predictors of adverse perinatal outcomes
Receiver operating characteristic analysis to assess predictive performance
Significant differences in albumin-based indices between preeclamptic and healthy pregnancies
44.1% of preeclamptic patients developed composite adverse perinatal outcomes
Only blood urea nitrogen-to-albumin ratio (BAR) was independently associated with adverse outcomes
BAR showed moderate discriminative performance (AUC = 0.718) for predicting outcomes