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May 7, 2026Journal of the American Chemical Society0 citations

Ligand-Enabled Pd-Catalyzed C(sp 3 )–H/C(sp 2 )–H Coupling

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HZHaiwei ZhaoZLZhen LiXZXinyu Zhu

Key Points

  • The research aims to explore Pd-catalyzed coupling reactions involving C(sp3)–H and C(sp2)–H bonds.
  • Utilized ligand-enabled Pd-catalysis for C(sp3)–H/C(sp2)–H coupling.
  • Investigated the reaction of C–H bonds with indoles and pyrroles as substrates.
  • Confirmed successful coupling of C(sp3)–H and C(sp2)–H bonds.
  • Identified pyrroles as effective reaction partners in the coupling process.

Abstract

)-H bonds with indoles and pyrroles as reaction partners.

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Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/69fbe357164b5133a91a282dhttps://doi.org/10.1021/jacs.6c03711
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