Association between the Loss of Ambulation and the Distal Aortic Diameter in Male Patients with Muscular Dystrophy: A CT-based Observational Study

Objective Muscular dystrophy (MD) is a rare neuromuscular disorder characterized by progressive muscle weakness and the loss of ambulation (LoA). Although vascular involvement has been suggested, the determinants of the aortic morphology in MD remain unclear. We hypothesized that the distal aortic diameters are smaller in patients with earlier LoA, potentially reflecting a reduced lower limb activity.