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May 7, 2026Stroke Vascular and Interventional NeurologyOpen Access

Consensus Guidelines on Inferior Petrosal Sinus Sampling: A Guideline From the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee

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Authors

FSFarhan SiddiqHBH. BrooksEDEsra Demirtas

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Overview

Guidelines standardize BIPSS procedures for Cushing disease assessment, highlighting risks and enhancing diagnostic yield.

Key Points

  • The aim is to establish standardized guidelines for inferior petrosal sinus sampling in Cushing disease.
  • A multidisciplinary panel developed recommendations using a systematic review and modified Delphi process.
  • Guideline includes indications for BIPSS, technical approaches, and sampling protocols.
  • Competency benchmarks and quality-assurance metrics are also defined.
  • Standardized BIPSS can provide high sensitivity and specificity for localizing ACTH pathologies.
  • Recommendations address pitfalls like false negatives and sampling errors.

Cite This Study

Siddiq et al. (2026) studied this question.

synapsesocial.com/papers/69fbe3ca164b5133a91a3119https://doi.org/10.1161/svin.125.002309
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