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May 7, 2026ANZ Journal of Surgery0 citations

Analysis of Voiding Impairment Following Transperineal Prostate Biopsy: Do Alpha‐Blockers Reduce the Risk?

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YZYi ZhengDYDong YeZCZhenghao Chen

Key Points

  • The research aims to evaluate the impact of alpha-blockers on voiding impairment following transperineal prostate biopsy.
  • Assessed voiding impairment and post-void residual urine in patients post-biopsy at 7 and 30 days.
  • Compared voiding parameters across groups with and without alpha-blocker pretreatment.
  • Performed logistic regression analyses to identify predictors of voiding impairment.
  • Patients without alpha-blocker pretreatment showed higher rates of voiding impairment (p < 0.05).
  • Alpha-blocker pretreatment for less than 12 months was protective against voiding impairment (p < 0.01).
  • Diabetes mellitus was identified as an independent risk factor for voiding impairment.

Abstract

BACKGROUNDS: ), and post-void residual urine. Follow-up assessments were performed at 7 and 30 days post-biopsy. The rate of voiding impairment and post-biopsy voiding parameters were compared across groups. Logistic regression analyses were conducted to identify independent predictors of post-biopsy voiding impairment. RESULTS: compared with patients without alpha-blocker pretreatment (p 12 months showed no differences in voiding impairment rate or voiding parameters compared to those without alpha-blocker pretreatment (p > 0.05). Logistic regression analyses demonstrated that diabetes mellitus (DM) was independently associated with post-biopsy voiding impairment, whereas alpha-blocker pretreatment for < 12 months exerted a protective effect (p < 0.01). CONCLUSION: TPPB is associated with voiding impairment. DM may serve as a predictor of post-biopsy voiding impairment, while alpha-blocker pretreatment for < 12 months may play a protective role.

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Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/69fbefa3164b5133a91a3947https://doi.org/10.1111/ans.70711
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