Significant Reduction in Hba1c Through Integrative Ayurvedic Management Including Panchakarma and Prameha Diet Therapy: An Observational Cohort Study

Background: Type 2 Diabetes Mellitus (T2DM) is a growing global health crisis. Ayurvedic Panchakarma-based therapies, combined with structured dietary intervention, have been traditionally used for Prameha management, but real-world clinical outcome data remain scarce. Objective: To evaluate the effect of an integrated Ayurvedic protocol comprising CDC Panchakarma (CDC-SP/CDC-KP), Prameha Diet Box, and individualized herbal medications on glycemic control, anthropometric parameters, blood pressure, and allopathic medication burden in T2DM patients. Methods: Retrospective observational cohort study of 56 T2DM patients (31 male, 25 female; mean age 53.1 ± 12.9 years). Pre- and post-intervention values were compared using paired Student's t-test. Results: HbA1c reduced significantly from 9.07 ± 2.01% to 7.52 ± 1.44% (mean reduction 1.55%; p < 0.0001; n=45). RBS reduced from 217.9 ± 96.3 to 173.9 ± 71.0 mg/dL (p = 0.0007). Body weight reduced by 2.83 kg (p < 0.0001). Complete cessation of allopathic medications was achieved in 21.4% of patients; 39.3% had partial reduction. Conclusion: Integrated Ayurvedic management produced statistically significant glycemic improvements and substantial reduction in allopathic medication dependence. Larger randomized trials are warranted.