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May 7, 2026SpineOpen Access

Cognitive Impairment in Patients with Degenerative Cervical Myelopathy

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Authors

HLHui LiJCJianing CuiJWJiayuan Wu

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Overview

Cross-sectional study reveals cognitive impairment in cervical myelopathy patients, indicating significant spinal cord compression effects.

Key Points

  • Examine cognitive impairment in degenerative cervical myelopathy and its relation to spinal cord compression.
  • Cross-sectional study involving 965 participants across three groups: DCM patients, CSR patients, and healthy controls.
  • Cognitive performance evaluated using MoCA, MMSE, and BCAT.
  • Propensity-score matching was applied to balance demographics and educational background.
  • Radiographic assessments of spinal cord compression were made via cervical MRI and correlation analyses conducted.
  • DCM patients had lower MoCA (20.61) and MMSE (26.23) scores compared to CSR and controls (P < 0.001).
  • Negative correlations were found between maximum spinal cord compression and cognitive scores (MoCA r = -0.118, MMSE r = -0.124; P < 0.05).
  • Lower cognitive scores persisted across all age and educational strata.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69fbf004164b5133a91a427fhttps://doi.org/10.1097/brs.0000000000005717
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