Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

Key Points

• The research aims to elucidate the crystal structure of macrophage migration inhibitory factor from Plasmodium vivax.
• Determined the crystal structure of PvMIF using X-ray diffraction techniques.
• Identified the biological unit as a typical MIF trimer.
• Revealed a single molecule in the asymmetric unit as part of the MIF trimer structure.
• Confirmed the biological unit of PvMIF functions as a prototypical trimer.

Abstract