Synergistic Silver Nanoparticle–Graphene Quantum Dot Composites in Silk Fibroin/Lathyrus Protein–Oxidized Alginate Hydrogels for Accelerated Diabetic Wound Healing

Key Points

• The aim is to enhance wound healing in diabetic patients using a composite hydrogel solution.
• Developed an injectable, self-healing hydrogel using silver nanoparticles and graphene quantum dots combined with silk fibroin and oxidized alginate.
• Evaluated the hydrogel's healing properties in a controlled environment.
• Assessed recovery metrics in diabetic wound models.
• The composite hydrogel significantly accelerated wound closure rates compared to standard treatments, with a notably higher percentage of healed wounds.
• Reduction in inflammation and improved tissue regeneration were observed in treated wounds, demonstrating enhanced healing characteristics.

Abstract