Antifungal metabolites from Myxococcus stipitatus GXUA 01510 for the control of sugarcane Pokkah boeng disease caused by Fusarium sacchari

Key Points

• To evaluate the antifungal activity of thiazole compounds against Fusarium sacchari, which causes Pokkah boeng disease in sugarcane.
• Evaluated the antifungal metabolites cystothiazole A and melithiazol F against Fusarium sacchari.
• Assessed effects on growth, spore germination, and cell membrane integrity of the pathogen.
• Cystothiazole A and melithiazol F significantly inhibited Fusarium sacchari growth and spore germination.
• Disruption of cell membrane integrity was observed with both thiazole compounds.

Abstract