Foetal-onset biventricular noncompaction with an MYH7 variant transitioned from prenatal right heart failure to progressive left heart failure at 5 months of age.
Case Report
No
1 case of foetal-onset biventricular noncompaction with an MYH7 variant
Clinical course (resolution of right heart failure and development of left heart failure)
Postnatal hemodynamic changes can influence the biventricular noncompaction phenotype in MYH7 variants, leading to a transition from fetal right heart failure to postnatal left heart failure.
Abstract We report a case of foetal-onset biventricular noncompaction with an MYH7 variant. Prenatal fetal hydrops and right heart failure resolved after birth, but progressive left heart failure developed at 5 months. This transition reflects how postnatal hemodynamic changes influence the biventricular noncompaction phenotype, necessitating vigilant monitoring for left heart failure in foetal-onset biventricular noncompaction cases with MYH7 variants.
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Yuya Yamada
Keiichi Hirono
Kazushi Yasuda
Cardiology in the Young
University of Toyama
Children's Medical Center
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Yamada et al. (Wed,) conducted a case report in Biventricular noncompaction with an MYH7 variant (n=1). Foetal-onset biventricular noncompaction with an MYH7 variant transitioned from prenatal right heart failure to progressive left heart failure at 5 months of age.
www.synapsesocial.com/papers/69fd7f3abfa21ec5bbf079db — DOI: https://doi.org/10.1017/s1047951126112980
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