Empirical Validation of RPCS-1: Measurement Pipeline, Power Analysis, and Two-Stage Validation Design

Methodological Proposal + Power Analysis + Two-Stage Validation Design. Specifies behavioral assays for each receiver primitive: TI via N-back/complex span tasks, SG via psychophysics detection thresholds and d', FT via Stroop/flanker/prepulse inhibition, UE via probabilistic reversal learning slopes, AR via forced choice under ambiguity. Statistical power: P2 testable at N~100 (single clinical site), P5 at N~300, P3 at N~1000, P1 at N~3000, P4 at N~30000 (epidemiological). Two-Stage Design: Stage 1 cross-sectional parameter estimation (N~700); Stage 2 longitudinal P2/P5 testing. Identifies laboratory consortia with relevant infrastructure: ABCD, UK Biobank, ENIGMA, HiTOP, Lifelines, Penn CNB. Makes RPCS-1 testable at population scale with current methods. Inherits from Paper 9.