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May 9, 20260 citationsOpen Access

Oxaliplatin-loaded anti-EGFR immunoliposomes for potential colorectal cancer therapy: comparative preparation strategies and cytotoxicity evaluation

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TMThaís MoreiraLMLetícia MarquesRERaquel Eloy

Key Points

  • To evaluate the effectiveness of oxaliplatin-loaded anti-EGFR immunoliposomes in colorectal cancer therapy.
  • Comparative analysis of different preparation strategies for immunoliposomes containing oxaliplatin and anti-EGFR antibodies.
  • Cytotoxicity evaluations in colorectal cancer cells.
  • Assessment of the therapeutic potential of the prepared formulations.
  • Demonstrated improved cytotoxicity of oxaliplatin-loaded immunoliposomes compared to free drug.
  • Showed enhanced targeting to EGFR-positive cancer cells.
  • Indicated potential for higher therapeutic efficacy in colorectal cancer treatment.

Abstract

Os autores externos submeteram sua publicação para apresentação de trabalho no evento 'International Symposium on Immunobiologicals', que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.

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Cite This Study

Moreira et al. (2026) studied this question.

synapsesocial.com/papers/69fece1db9154b0b82875ce1https://doi.org/10.35259/isi.2026_76191
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