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May 9, 2026Open Access

Optimization of alkali-ethanol fractionation of Miscanthus using response surface methodology

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Authors

HCHalim ChooNCNiclas ConenMDMoritz Doeker

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Overview

Randomized trial optimizes pulp yield and delignification in Miscanthus, indicating a pathway for sustainable biorefineries.

Key Points

  • The aim is to optimize the alkali-ethanol fractionation process of Miscanthus × giganteus for sustainable production.
  • Used Box-Behnken Design (BBD) to screen four independent variables at low severity.
  • Employed Central Composite Design (CCD) to optimize temperature and alkali concentration at high severity.
  • Conducted chemical and morphological analyses to confirm results.
  • In low severity, optimal polysaccharide yield achieved 73.3% with 96.9% cellulose retention, 92.2% xylan retention; 83.1% lignin removal for delignification.
  • In high severity, polysaccharide yield resulted in 88.2% cellulose and 67.6% xylan retention, with 91.3% lignin removal for delignification.

Cite This Study

Choo et al. (2026) studied this question.

synapsesocial.com/papers/69fecf71b9154b0b828766c7https://doi.org/10.34734/fzj-2026-02210
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