Furan-2-Carboxamides as Dienes in Cascade SN2’/Intramolecular Diels-Alder Reaction with MBH Carbonates

Key Points

• The study aims to evaluate the Lewis base-initiated cascade SN2’/Diels-Alder reaction using furan-2-carboxamides.
• Utilized Morita–Baylis–Hillman carbonates as substrates.
• Implemented Lewis base initiation for the reaction.
• Evaluated yields of the resulting polycyclic lactams.
• Achieved up to 99% yield in the transformation.
• Successfully constructed densely functionalized polycyclic lactams.