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May 9, 2026American Journal of Neuroradiology0 citationsOpen Access

In Vivo Visualization of the Round Window Niche Veil using Photon-Counting Detector CT

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KNKaden M. NeubergerPFPaul F. FarnsworthJLJohn I. Lane

Key Points

  • This research aims to assess the effectiveness of photon-counting detector CT in visualizing the round window niche veil.
  • 80 PCD-CT scans of temporal bones were analyzed between April and June 2025.
  • Two neuroradiologists independently scored the scans based on visibility of the RWNV.
  • Scoring categories included partial visibility, complete visibility, no visibility, and complete opacification.
  • PCD-CT visualized the RWNV in 43.8% of ears.
  • The RWNV was not visualized in 48.8% of ears with a clear round window.
  • Inter-rater reliability was high with an unweighted kappa of 0.81.

Abstract

BACKGROUND AND PURPOSE: The round window niche veil (RWNV) is a potential anatomic barrier at the round window niche due to thickened middle ear mucosa or fibrosis that either partially or completely covers the niche and may prevent intratympanic medication efficacy. This study aimed to characterize the in vivo capability of photon-counting-detector (PCD) CT to visualize the RWNV. MATERIALS AND METHODS: 80 PCD-CT temporal bones were included in the study between April and June 2025. Two experienced neuroradiologists independently reviewed each scan and assigned each with one of the following scores: 1: partial veil seen with or without fluid, 2: complete veil seen with or without fluid, 3: no round window niche veil, and 4: not seen, complete round window niche opacification. RESULTS: PCD-CT visualized either partial or complete RWNV in 43.8% of ears. Further, the RWNV was not visualized in 48.8% of ears when the round window was clear. In 7.5% of ears, complete opacification of the round window niche was noted without visualization of a RWNV. The presence or absence of RWNV visualization demonstrated high inter-rater reliability with unweighted kappa of 0.81 (0.69, 0.92). CONCLUSIONS: PCD-CT may visualize the round window niche veil in vivo and may be helpful in determining if the round window niche is patent.

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Cite This Study

Neuberger et al. (2026) studied this question.

synapsesocial.com/papers/69fed0abb9154b0b82877b8fhttps://doi.org/10.3174/ajnr.a9399
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