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March 26, 2021Frontiers in Cell and Developmental Biology21 citationsOpen Access

Sycp1 Is Not Required for Subtelomeric DNA Double-Strand Breaks but Is Required for Homologous Alignment in Zebrafish Spermatocytes

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YIYukiko ImaiKSKenji SaitoKTKazumasa Takemoto

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Abstract

mutant spermatocytes, suggesting that Iho1 dissociation from axes occurs in a DSB-dependent manner. Our results demonstrated that Sycp1 is not required for peritelomeric DSB formation but is necessary for complete pairing of homologs in zebrafish meiosis.

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Imai et al. (2021) studied this question.

synapsesocial.com/papers/69ff9ae56be84a7ac88549e7https://doi.org/10.3389/fcell.2021.664377
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