What question did this study set out to answer?

This research aims to examine the independent and combined effects of noise exposure and gestational hypertension on the risk of preterm birth among female workers.

May 10, 2026China CDC Weekly0 citationsOpen Access

Propensity Score Matching Analysis on Interaction Between Noise Exposure and Gestational Hypertension for Preterm Birth Among Female Workers — 4 PLADs, China, 2024−2025

LALi Aihua MZMeibian Zhang YCYu Changyan

Key Points

This research aims to examine the independent and combined effects of noise exposure and gestational hypertension on the risk of preterm birth among female workers.
Used propensity score matching (PSM) to analyze data from 7,886 female manufacturing and mining workers.
Utilized logistic regression to assess the relationship between noise exposure, gestational hypertension, and preterm birth risk.
Identified preterm birth prevalence and conducted interaction analysis for combined exposure effects.
Overall preterm birth prevalence was 9.3%.
Occupational noise and gestational hypertension independently increased preterm birth risk, with aOR=4.06 (95% CI: 2.14, 7.70).
The additive interaction indicated a relative excess risk of interaction (RERI)=1.11, attributable proportion (AP)=27.34%, and synergy index (S)=1.57.

Abstract

What is already known about this topic? Preterm birth (PTB) is a major public health concern. While noise exposure and gestational hypertension (GH) are recognized risk factors for PTB, evidence on their independent and combined effects among female workers remains limited. What is added by this report? Using PSM and logistic regression in 7,886 female manufacturing and mining workers, this study confirmed an overall PTB prevalence of 9.3%. Occupational noise and GH independently elevated PTB risk, with a significant positive additive interaction and the highest risk in the co-exposed group adjusted odds ratio (aOR)=4.06, 95% (CI): 2.14, 7.70; relative excess risk due to interaction (RERI)=1.11, attributable proportion (AP)=27.34%, synergy index (S)=1.57. What are the implications for public health practice? Targeted, integrated public health interventions are needed to reduce PTB risk among female workers, including occupational noise control in manufacturing and mining settings, routine GH screening and management during pregnancy, and enhanced surveillance for workers exposed to both risk factors.

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