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May 10, 2026BMJ Open Quality0 citationsOpen Access

Closed-Loop Management of Body Fluid Specimens in Hospitalized Patients

Closed loop full process management and application of body fluid specimens in hospitalised patients

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Authors

DZDan ZhaoYPYingxin PengJWJie Wang

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Overview

Randomized trial demonstrates improved submission timeliness and specimen quality in hospitalized patients, suggesting enhanced patient safety.

Key Points

  • The aim is to develop a closed-loop management system for improving body fluid specimen handling in hospitalized patients.
  • Established a multidisciplinary inpatient specimen management team to identify inefficiencies.
  • Implemented targeted interventions in February 2025 based on the team's analysis.
  • Compared preanalytical turnaround times and unqualified specimen rates before and after implementation.
  • Delayed submission rate decreased from 15.62% to 5.8%, p<0.05.
  • Unqualified specimen rate decreased from 0.70% to 0.39%, p<0.05.
  • Significant improvements were observed at 3 and 6 months post-intervention, p<0.05.
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Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/6a0020aec8f74e3340f9b783https://doi.org/10.1136/bmjoq-2025-003740
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