This review illustrates innovative therapies aimed at restoring vision in various retinal diseases and optic neuropathies, highlighting their mechanisms and challenges.
Key Points
The aim is to provide a comprehensive overview of current therapies for vision restoration in optic neuropathies and retinal diseases.
Overview of the visual pathway and imaging modalities
Discussion of four vision restoration approaches: gene therapy, stem cell therapy, optogenetics, and retinal prosthetics
Evaluation of clinical outcomes and limitations for each therapeutic method.
Gene and stem cell therapies show potential in repairing damaged retinal cells, though challenges remain
Retinal prosthetics can induce visual experiences, but face limitations in resolution
Electrical stimulation techniques have demonstrated ability to enhance residual vision through neuroprotective measures.