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January 31, 2026Heart Lung and Circulation0 citations

Discharge Timing of Patients Presenting With ST-Segment Elevation Myocardial Infarction: A Regional Experience

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KTK. ThawATAdam TrytellACAndrew Cobden

Key Result

Early hospital discharge (<72 hours) after STEMI and primary PCI was associated with a 1.5% rate of major adverse cardiovascular events compared to 1.2% for standard discharge (p=0.616).

Key Points

  • The aim is to evaluate patient characteristics and outcomes based on hospital discharge timing after STEMI and PCI.
  • Retrospective analysis of patients presenting with STEMI at a PCI center in regional Victoria, Australia between January 2022 and December 2022.
  • Patients were categorized into early discharge (<72 hours), standard discharge (3-5 days), and late discharge (>5 days) groups.
  • Data on demographics, procedural outcomes, and 30-day readmissions were collected and compared.
  • Early discharge group had 1.5% major adverse cardiovascular event rate, similar to standard (1.2%) and higher than late (4.2%) discharge groups (p=0.616).
  • Hospital readmission rates were 13.2% for early discharge and 14.8% for standard discharge (p=0.411).
  • Patients with early discharge had higher rates of right coronary artery or left circumflex culprit vessel and lower incidences of left ventricular systolic dysfunction.

Study Design

Type

Cohort

Multicenter

No

Structured PICO

Does early hospital discharge (<72 hours) maintain safety outcomes compared to standard or late discharge in patients presenting with STEMI treated with primary PCI?

P
Population
Consecutive patients presenting with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) at a 24/7 regional centre in Victoria, Australia.
I
Intervention
Early hospital discharge (<72 hours)
C
Comparator
Standard discharge (3-5 days) and late discharge (>5 days)
O
Outcome
30-day hospital readmission, major adverse cardiovascular events (MACE), and mortality rateshard clinical

Early hospital discharge (<72 hours) appears safe for uncomplicated STEMI patients post-PCI, particularly those with non-LAD culprit lesions, without increasing 30-day readmission or MACE.

Main Result

Absolute Event Rate: 1.5% vs 1.2%

p-value: p=0.616

Abstract

BACKGROUND In regional settings, early hospital discharge after primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) could improve efficiency of healthcare systems. AIM This study aimed to assess the characteristics of patients after STEMI and PCI based on hospital length of stay and compare the differences in outcomes of patients according to their length of hospital stay. METHOD We performed a retrospective analysis of consecutive patients presenting with STEMI to our 24/7 PCI centre in regional Victoria, Australia between January 2022 and December 2022. Baseline patient characteristics, procedural data, and outcome data including 30-day hospital readmission, major adverse cardiovascular events, and mortality rates were collected. Patient data were compared between three groups: early discharge (5 days). RESULTS The early hospital discharge group had higher rates of a right coronary artery or left circumflex culprit vessel, with lower incidences of left ventricular systolic dysfunction. The major adverse cardiovascular event rate in the early discharge group was 1.5% compared with the standard and late discharge groups with 1.2% and 4.2%, respectively (p=0.616). The rates of hospital readmission of any type were similar between early discharge group and standard discharge group (13.2% and 14.8%, respectively; p=0.411). CONCLUSIONS In patients treated successfully with PCI after non-left anterior descending artery STEMI with an uncomplicated postprocedural course, early discharge may be safely achieved.

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Cite This Study

Thaw et al. (2026) conducted a cohort in ST-segment elevation myocardial infarction (STEMI). Early discharge (<72 hours) vs. Standard discharge (3-5 days) and late discharge (>5 days) was evaluated on Major adverse cardiovascular events (p=0.616). Early hospital discharge (<72 hours) after STEMI and primary PCI was associated with a 1.5% rate of major adverse cardiovascular events compared to 1.2% for standard discharge (p=0.616).

synapsesocial.com/papers/6a0258fd45880192ae423ceahttps://doi.org/10.1016/j.hlc.2025.08.020
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Discharge after primary percutaneous coronary intervention: the earlier the better?2021 · 3 citations
  2. 2Early Discharge After ST-Segment Elevation Myocardial Infarction2021 · 9 citations
  3. 3Very Early Discharge After Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: Mortality Outcomes at Six Months2022 · 10 citations
  4. 4Safety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction: A meta-analysis of randomised controlled trials2018 · 43 citations
  5. 5Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries2009 · 667 citations