What question did this study set out to answer?

The aim is to evaluate the effectiveness of the LIRA sizing method for transcatheter aortic valve replacement in patients with forme fruste bicuspid aortic valve.

February 28, 2026Structural Heart0 citationsOpen Access

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Transcatheter Aortic Valve Replacement in Forme Fruste Bicuspid Aortic Valve With the Dedicated LIRA Sizing Method

GZGreca Zanda BBBárbara Bellini VRVittorio Romano

Key Result

The LIRA sizing method for TAVR in patients with forme fruste bicuspid aortic valve led to frequent prosthesis downsizing, achieving 100% technical success and 97.6% device success.

Key Points

The aim is to evaluate the effectiveness of the LIRA sizing method for transcatheter aortic valve replacement in patients with forme fruste bicuspid aortic valve.
Evaluated 43 patients undergoing transcatheter aortic valve replacement (TAVR) using the LIRA sizing method.
Identified forme fruste bicuspid aortic valves with full-cycle CT imaging.
Assessed technical and device success rates.
Achieved 100% technical success rate in TAVR procedures.
Reported a device success rate of 97.6% after implantation.
Frequent prosthesis downsizing was noted during the procedure.

Structured PICO

Does the LIRA sizing method yield high technical and device success in patients with forme fruste bicuspid aortic valve undergoing TAVR?

Population

43 patients with forme fruste bicuspid aortic valve undergoing Transcatheter Aortic Valve Replacement (TAVR)

Intervention

Transcatheter Aortic Valve Replacement (TAVR) using the dedicated LIRA sizing method

Outcome

Technical success and device success

The dedicated LIRA sizing method for TAVR in patients with forme fruste bicuspid aortic valve yields high technical and device success rates.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

• Forme fruste bicuspid aortic valve: often underrecognized phenotype, can be identified with full-cycle CT. • LIRA sizing method in 43 TAVR patients led to frequent prosthesis downsizing with 100% technical and 97.6% device success. • Dedicated BAV sizing appears beneficial even in this subtle BAV phenotype. Figure: see text

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Transcatheter Aortic Valve Replacement in Forme Fruste Bicuspid Aortic Valve With the Dedicated LIRA Sizing Method

Key Result

Key Points

Structured PICO

Main Result

Abstract

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